Aim To determine changes in global DNA methylation in monocytes from neonates of women with obesity, as markers of an immune programming resulting from maternal obesity. Materials & methods Cord blood monocytes were obtained from neonates born to women with obesity and normal weight, genome-wide differentially methylated CpGs were determined using…[Read more]

performances or even earlier, after being genotyped using a reference population of CB animals.Behavioral changes caused by domestication in animals are an important issue in evolutionary biology. The silkworm, Bombyx mori, is an ideal fully domesticated insect model for studying both convergent domestication and behavior evolution. We explored…[Read more]

001) with the highest rate (78%) in the HR-/HER2+ group. Overall, HER2+ patients had a significantly higher AXpCR than HER2- subtypes (66% versus 28% P<0.001). HR and HER2 status were also predictive of AXpCR when comparing patient, tumor, and treatment variables.

Biologic subtype better correlated with rates of AXpCR than nodal burden…[Read more]