Rationale High-intensity focused ultrasound (HIFU) therapy represents a noninvasive surgical approach to treat uterine fibroids. The operation of HIFU therapy relies on the information provided by medical images. In current HIFU therapy, all operations such as positioning of the lesion in magnetic resonance (MR) and ultrasound (US) images are…[Read more]

Characteristics of a beam-shaping assembly that utilizes photo-neutrons from irradiation of a tungsten target by electrons from an accelerator were examined to produce a beam of neutrons suitable for boron neutron capture therapy. The epithermal neutron flux per kilowatt of electron-beam power almost increased to a maximum as the energy of the…[Read more]

05). CONCLUSIONS The degree of pain in pancreatic cancer is closely related to the pathological stage and expressions of NF-κB and COX-2, and the expressions of NF-κB and COX-2 are raised and the pain is aggravated as well in the patients at a higher pathological stage.PURPOSE Systemic inflammation plays a crucial role in carcinogenesis and p…[Read more]

An efficient process for recycling waste LiMn2O4 cathode material is proposed in this research. This report constitutes low-temperature (NH4)2SO4 calcination mechanisms and water-leaching characteristics of the calcined samples. A calcination temperature range of 420.65-634.12 °C is determined by analysis of the TG-DSC curve under the conditions…[Read more]

Lsd1 inhibitor treatment also blocked Slug-stimulated lipogenesis. Remarkably, hepatocyte-specific deletion of Slug inhibited the hepatic lipogenic program and protected against obesity-associated NAFLD, insulin resistance, and glucose intolerance in mice. Conversely, liver-restricted overexpression of Slug, but not the Lsd1 binding-defective Slug…[Read more]

959 reviews were requested by the GPs or 74 cards per month. The cardiologists were solicited 2.3 times a month. The cardiologist rated the ECG abnormal or doubtful for 31.9% of exams. An appointment was scheduled on average within 24 days. Few difficulties in using the service have been reported by users. Discussion The results show that…[Read more]

0 °C-days at both depths, which were coincidental with a mass coral bleaching event. This eddy’s impact was additionally evident in high correlations between daily temperature minima and residual sea levels, suggesting that mesoscale eddies alter stratification, substantially influence temperature variation, and play important roles in…[Read more]

This systemic review and meta-analysis aimed to investigate the burden of tuberculosis immune reconstitution syndrome (TB-IRIS) and associated mortality to highlight the importance of future direction in preventing and treatment of TB-IRIS. Randomized clinical trials (RCTs) that compared early antiretroviral therapy (ART) versus late ART were…[Read more]

Maintenance of physiologically balanced levels of autophagy is crucial for cellular homeostasis and in the normal vessel wall, balanced autophagy can be considered a cytoprotective mechanism that preserves endothelial function and prevents cardiovascular disease. Recent studies pointed out the importance of the modulation of the autophagic flux in…[Read more]

Food and Drug Administration (FDA) has approved a drug product (Spritam®) and many medical devices manufactured by three-dimensional printing (3DP) processes for human use. There is immense potential to print personalized medicines using 3DP. Many 3DP methods have been reported in the literature for pharmaceutical applications. However, selective…[Read more]

For recent decades, non-fullerene acceptors (NFAs) are undergoing rapid development and emerging as a hot area in the field of organic solar cells. Among the high performance nonfullerene acceptors, aromatic diimide based electron acceptors remain to be the highly promising systems. This review discusses the important progress of perylene diimide…[Read more]