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  • Santiago Wentworth posted an update 11 hours, 7 minutes ago

    In particular, large numbers of patients are needed for brain imaging and genetic studies. To meet these requirements, a number of networks and groups in the field of TS have developed over the years creating an efficient, lively, and supportive international research community. In this review, we will provide an overview of these groups and networks.Introduction This study aimed to analyze the clinical features of myasthenia gravis (MG) in combination with the afterdischarges and compare the characteristics of afterdischarges in MG with different serum antibodies. find more Methods Ninety-two patients with MG were analyzed retrospectively. The afterdischarges were investigated using motor nerve conduction examination, F-wave examination, and repetitive nerve stimulation (RNS). Results Afterdischarges were observed after the M wave in 14 of 92 patients. Three of these 14 patients tested positive for the muscle-specific tyrosine kinase antibody (MuSK-Ab), and 11 patients tested positive for the acetylcholine receptor antibody (AchR-Ab). The characteristics of the afterdischarges on RNS differed distinctly between the two antibody groups. The afterdischarges occurred on the first stimulation, but decreased on the second and subsequent stimulations in patients with MuSK-MG, while the afterdischarges continued to occur on each stimulation in patients with AchR-MG. Discussion The characteristics of the afterdischarges on RNS enabled easy identification of their synaptic or neurogenic nature.Load monitoring in basketball is fundamental to develop training programs, maximizing performance while reducing injury risk. However, information regarding the load associated with specific activity patterns during competition is limited. This study aimed at assessing the external load associated with high-intensity activities recorded during official basketball games, with respect to different (1) activity patterns, (2) playing positions, and (3) activities performed with or without ball. Eleven male basketball players (six backcourt, five frontcourt, age 20.5 ± 1.1 years, stature 191.5 ± 8.7 cm, body mass 86.5 ± 11.3 kg; experience 8.5 ± 2.4 years) competing in the Lithuanian third division were recruited for this study. Three in-season games were assessed via time-motion analysis and microsensors. Specifically, the high-intensity activities including sprints, high-intensity specific movements (HSM) and jumps were identified and subsequently the external load [PlayerLoad™ (PL) and PlayerLoad™/min (PL/min)]current findings suggest that external load differences in high-intensity activities exist among activity patterns and between activities performed with and without ball, while no differences were found between playing positions. Practitioners should consider these differences when designing training sessions.Eyewitnesses are often susceptible to recollection failures and memory distortions. These failures and distortions are influenced by several factors. The present review will discuss two such important factors, attention failures and stress. We argue that acute stress, often experienced by eyewitnesses and victims of crimes, directly influences attentional processes, which likely has downstream consequences for memory. Attentional failures may result in individuals missing something unusual or important in a complex visual field. Amongst eyewitnesses, this can lead to individuals missing details, even unusual or important central details, regarding the crime. Surprisingly, few studies have investigated attentional failures in eyewitness scenarios, and none have investigated the relationship between stress, attention, and witness memory. This review will discuss the impact of attentional failures, mainly those resulting from inattentional blindness, in applied contexts in order to bridge to eyewitness scenarios. In addition, we will integrate the applied literature on attentional failures with literature that examines the influences of arousal and stress on attention. We will conclude by presenting how future research may tease apart the independent contributions of arousal and stress on attentional failures and successes and how this research may inform understanding of eyewitness reliability.This article seeks to provide a theoretical exploration of Prandi’s model of conceptual conflicts in metaphors (2017) and to highlight the advantages such model presents in its applications to translation and the text analysis preceding and preparing translation. Such advantages are mainly identified in the model aptness to meet the pragmatic requirements of translation, seen as a practice-based, goal-oriented and context-driven activity. These advantages also distinctly emerge from a comparison with the main tenets of the cognitive tradition. The theoretical basis for an understanding of conceptual conflict and its applications to translation are illustrated through the analysis of three brief excerpts from literary texts in English and their Italian translation.The coronavirus disease 2019 (COVID-19) has taken the world by surprise and has impacted the lives of many, including the business sector and its stakeholders. Although studies investigating the impact of COVID-19 on the organizational structure, job design, and employee well-being have been on the rise, fewer studies examined the role of leadership and what it takes to be an effective leader during such times. This study integrates social cognitive theory and conservation of resources theory to argue for the importance of adaptive personality in the emergence of effective leaders during crisis times, utilizing the crisis of COVID-19 as the context for the study. We argue that managers with an adaptive personality tend to have increased self-efficacy levels to lead during a crisis, resulting in increased motivation to lead during the COVID-19 crisis. Furthermore, managers with increased motivation to lead during the COVID-19 crisis are argued to have enhanced adaptive performance, thereby suggesting a serial mediation model where crisis leader self-efficacy and motivation to lead during the COVID-19 crisis act as explanatory mechanisms of the relationship between the adaptive personality and performance of the manager. In order to test our hypotheses, we collected data from 116 full-time managers in Saudi Arabia during the COVID-19 crisis and used hierarchical linear regression as the method of analysis. The findings support all of the hypotheses. A discussion of the results, contributions, limitations, and future directions is included.

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