Background As one of the novel therapeutic drugs that targets Calcitonin gene-related peptide (CGRP), 75 mg rimegepant has been used for the acute management of migraine, which is one of the most common neurological diseases worldwide. see more Several clinical trials have been conducted to investigate the efficacy and safety of rimegepant for the…[Read more]

Conclusion Our data demonstrate the protective effect of SLIGRL in airways; however, this effect appears to be mediated independently of prostanoids, nitric oxide, circulating adrenaline, ATP-sensitive K + channels, and vagal stimulation. Copyright © 2019 Journal of Microscopy and Ultrastructure.Mesenchymal tumors of the thyroid are extremely…[Read more]

This adsorbent after saturated adsorption could be rapidly separated from water due to its enlarged density after embedded silica sand; moreover, those rapidly recovered adsorbents were tried to use as new adsorbents for removal of an anionic dye from water due to the complete changes in their surface structures after saturated adsorption.…[Read more]

3% versus 2.3%) and the uterine cancer groups (13.4% versus 5.8%), but not in the ovarian cancer (17.6% versus 15.1%) and the vulvar cancer groups (10.8% versus 13.1%). Similar findings were obtained for the proportion of gynecological practices that issued at least one HRT prescription. CONCLUSION HRT prescriptions significantly decreased after…[Read more]

5 months. A nonsignificant postoperative eGFR decrease of 3.0 ml/min/1.73m2 was found overall (P = 0.094), with nonsignificant difference between the 2 groups (P = 0.735). A comparable 5-year OS was calculated for RNU and SU patients (P = 0.99). CONCLUSIONS The type of surgery (SU vs. RNU) has a low impact on postoperative renal function an…[Read more]

004). No significant differences were observed between TZ and donepezil. No significant differences of adverse events were found. CONCLUSIONS TZ and donepezil could bring symptomatic benefit for mild to moderate VaD. Trial registration The protocol had retrospectively registered at clinical trial.gov, Unique identifier NCT02453932, date of…[Read more]

05, 95% CI 1.01-4.18). Compared to those who did not have any fast-food in the past week, the odds of reporting sleep disturbance was 2.6 times higher among those who had fast-food ≥3 days during the past week (OR 2.64, 95% CI 1.33-5.24). Adolescents who had high intake of both fast-food and soft drink had 3.4 times higher odds of reporting s…[Read more]

The development of polymers with built-in sensors that provide readily perceptible optical warning signs of mechanical events has received considerable interest. A simple and versatile concept to bestow polymers with mechanochromic behavior is the incorporation of dye-filled microcapsules. Such capsules release their cargo when their shell is…[Read more]

Individuals suffering from pathological gambling (PG) show impaired decision making, but it is still not clear how this impairment is related to other traits and neuroanatomical characteristics. In this study, we investigated how the influence of PG on decision making (1) is connected to different impulsivity facets and (2) how it is related to…[Read more]

resection without reduction is needed and surgery should be done following oncological principles. Copyright © 2020 Nigerian Journal of Surgery.Aim Tracheomalacia is a potentially life-threatening, but a rare complication of thyroidectomy. In previous studies, the incidence rate was very different. Considering the relatively high prevalence of…[Read more]