Whole-animal fluorescence cryo-imaging is an established technique that enables visualization of the biodistribution of labeled drugs, contrast agents, functional reporters and cells in detail. However, many tissues produce endogenous autofluorescence, which can confound interpretation of the cryo-imaging volumes. We describe a multi-channel,…[Read more]

lanet, which allows estimation of cell composition directly from placental DNAm data.

Despite marked recent improvements in long-read sequencing technology, the assembly of diploid genomes remains a difficult task. A major obstacle is distinguishing between alternative contigs that represent highly heterozygous regions. If primary and…[Read more]

Under current threats, even the more common species are in peril, calling for a reevaluation of hazards and conservation strategies that traditionally target already rare and endangered species only.Although widespread declines in insect biomass and diversity are increasing concerns within the scientific community, it remains unclear whether…[Read more]

The most preferred rewards included continuing education credits, professional growth opportunities, maintaining professional relationships with the university, and financial remuneration. To provide NP students with positive and effective clinical experiences, it is essential that NP program leaders understand preceptors’ preferences and commit…[Read more]

To minimize the contribution of FV inactivation by APC in vivo, a tail clip assay was performed in homozygous HA/FV Leiden (FVL) mice infused with FVIII-QQ or FVIII-WT in the presence or absence of monoclonal antibody 1609, an antibody that blocks murine PC/APC hemostatic function. FVIII-QQ again demonstrated enhanced hemostatic function in HA/FVL…[Read more]

Data were analysed using Spearman’s correlation, Wilcoxon’s signed-rank test, Cronbach’s alpha, Intra-class Correlation Coefficient (ICC), independent t-test and one-way ANOVA at p<0.05.

respondents’ domains scores on SS-QoL(E) and SS-QoL(I) did not differ significantly except in mobility and work (r=0.58 to 0.87; p=0.001). Cronbach’s…[Read more]

Surfactants are commonly found in today’s world as an essential component of cleaning detergents, cosmetics and drug delivery systems. They can penetrate into lipid membranes, thus changing their properties. The aim of this paper is to compare the effect of addition of small amounts of cationic (DTAB) and anionic surfactants (SDS) with the same…[Read more]