Posttranslational modifications, such as phosphorylation, are a powerful means by which the activity and function of nuclear receptors such as LXRα can be altered. However, despite the established importance of nuclear receptors in maintaining metabolic homeostasis, our understanding of how phosphorylation affects metabolic diseases is limited.…[Read more]

In this review, the authors discuss the available data regarding the use of peroral cholangioscopy in patients with PSC, with a focus on its use in the evaluation and management of biliary strictures and stones.Helicobacter pylori has several virulance factor i.e. VacA, CagA, BabA, SabA, AlpA, AlpB and etc. VacA has several polymorphic region in…[Read more]

women farmers had low awareness of zoonotic diseases. In conclusion, the priorities of national disease control programs do not fully match priorities of farmers. Such participatory tools should therefore, play a pivotal role when designing sustainable livestock health interventions. Copyright © 2019 Alemu, Desta, Kinati, Mulema, Gizaw and…[Read more]

Comprehensive care plans are dynamic documents maintained by an interdisciplinary team that contain specific, actionable information for clinicians and staff across multiple care settings. They promote communication and continuity of care by suggesting communication strategies, medical plans, and psychosocial resources. This article describes the…[Read more]