A method for pre-processing biological samples, high-resolution LC-MS instrumentation data, and qualitative software was established in this study to identify metabolite structures, laying the foundation for the study of the active ingredients and in vivo pharmacodynamics forms of Chinese medicines.Enzyme-linked immunosorbent assay(ELISA) and…[Read more]

Preeclampsia is a life-threatening multiorgan systemic disease with manifestations including gestational hypertension, oxidative stress, and vascular dysfunction. We aimed to evaluate the therapeutic effects of melatonin on an L-NAME (NLG-nitro-l-arginine methyl ester)-induced rat preeclampsia model. During gestation, L-NAME was added to drinking…[Read more]

Purpose The COVID-19 pandemic has been responsible for thousands of deaths worldwide. Testing remains at a premium, and criteria for testing remains reserved for those with lower respiratory infection symptoms and/or a known high-risk exposure. The role of imaging in COVID-19 is rapidly evolving; however, few algorithms include imaging criteria,…[Read more]

euronal autophagy via up-regulating the expression of Beclin-1 and LC3 Ⅱ/Ⅰ.OBJECTIVE To compare the therapeutic effect of shallow and deep needling at “Neiguan”(PC6) in the treatment of arrhythmia in rabbits. METHODS Male New Zealand rabbits were randomly divided into saline (n＝15), model (n＝12), shallow needling (n＝13) and deep needling (n＝12) gr…[Read more]