The purpose of this study was to evaluate the usefulness of the sonographic characteristics of papillary thyroid carcinoma (PTC) with Hashimoto’s thyroiditis (HT) for predicting central lymph node metastasis (CLNM). One hundred thirty-three patients who underwent thyroidectomy and central cervical lymph node dissection for PTC with coexistent HT…[Read more]

A hexanucleotide repeat expansion in the C9orf72 gene is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). How this mutation leads to these neurodegenerative diseases remains unclear. Here, we show using patient stem cell-derived motor neurons that the repeat expansion impairs microtubule-based…[Read more]

Moreover, unlike the case of [Formula see text], for [Formula see text] discontinuous phase transitions survive under the quenched disorder, although they are less sharp than under the annealed one.A new photoionization scheme accessible by Rhodamine dye lasers is proposed for the isotope separation of 176Lu.[Formula see text][Formula see text]…[Read more]

Cytochrome P450 enzymes (CYPs) play an essential role in the bio-transformation of polychlorinated biphenyls (PCBs). The present work implemented quantum mechanic/molecular mechanic methods (QM/MM) and density functional theory (DFT) to study the metabolic activation of 2,2′,3,3′,6,6′-hexachlorobiphenyl (PCB136) catalyzed by CYP2B6. Electrophilic…[Read more]