t difference at the 5-year follow-up compared to before treatment.

A high concentration of glycolic acid significantly improved skin roughness as well as follicular hyperpigmentation of patients with keratosis pilaris. The treatment was relatively safe, but there was no significant difference at the 5-year follow-up compared to before…[Read more]

For patients indicating acceptable pain, the mean NRS was 1.6 (n=21,010). Although the presence of pain recorded in the patient record increased substantially over the year, the percentage of reported interventions only slightly increased.

The (non) acceptable pain evaluation seems a valuable addition to the NRS for assessing pain among…[Read more]

Sea anemones of the genus Bunodosoma possess along their body column, longitudinally arranged brown-colored vesicles. We have shown that in B. cangicum, these warty structures contain a mixture of potent toxins. This work highlights the neuro-inhibitory effects exhibited by two decapod crustacean species exposed to the extracts from these…[Read more]

The objective/subjective excyclotorsional angles of the paretic eye were significantly larger than of the non-paretic eye only in group B.

In USOP the angle of excyclotorsion in the dominant eye is smaller than in the non-dominant eye. This may imply that the vertical sense of visual space is mainly adapted to the dominant eye, keeping the…[Read more]

In non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutation, the prognostic impact of a concurrent Phosphoinositide-3-kinase catalytic alpha polypeptide (PIK3CA) mutation was still unknown. Some studies have shown that EGFR mutant NSCLC patients treated with EGFR tyrosine kinase inhibitors (TKIs) when…[Read more]

We also indicated that propofol 1-hydroxyl might have contributed to interaction with wider targets among our body. INTRODUCTION The myofibroblast is a gastrointestinal stromal cell that is a target of tumor necrosis factor-alpha (TNF-α), a pro-inflammatory cytokine strongly implicated in colitis-associated cancer. Crosstalk between TNF-α and o…[Read more]

CONCLUSIONS Studies analyzing anti-trans stigma should concretely define anti-trans stigma. There is a need to develop measures of anti-trans stigma at all socioecological levels informed by the lived experiences of trans people. Sleep quality (SQ) is considered to be a critical variable in major depressive syndrome (MD) as well as in burnout…[Read more]

Protein flexibility and disorder is emerging as a crucial modulator of chromatin structure. Histone tail disorder enables transient binding of different molecules to the nucleosomes, thereby promoting heterogeneous and dynamic internucleosome interactions and making possible recruitment of a wide-range of regulatory and remodeling proteins. On the…[Read more]

05). SCZ could potentially alter the auditory spatial function, which may appear in the form of auditory neglect and extinction on the right side, depending on the characteristics of patient population.Avian influenza surveillance is a requirement for commercial trade in ostrich products, but influenza A viruses (IAVs) have proven difficult to…[Read more]

OBJECTIVES To measure the use of healthcare services and assistive devices by centenarians in five countries. DESIGN Cross-sectional study using a survey questionnaire. SETTING Community-dwelling and institutionalised centenarians living in Japan, France, Switzerland, Sweden and Denmark. PARTICIPANTS 1253 participants aged 100 or in their 100th…[Read more]