In summary, DeDFR1 and DeDFR2 are considered to be a new type of DFR with unique structures and functions. The discovery of the Arg-type DFR provides new insights into the anthocyanin biosynthesis pathway in ferns.BACKGROUND Cortisol has been used to capture psychophysiological stress during childbirth and postpartum wellbeing. We explored the…[Read more]

To summarize significant research contributions on ethics in medical informatics published in 2019.

An extensive search using PubMed/Medline was conducted to identify the scientific contributions published in 2019 that address ethics issues in medical informatics. The selection process comprised three steps 1) 15 candidate best papers were…[Read more]

With these developments, the “flipped operating room” was shown to be effective in improving knowledge and competence among undergraduate dental students. Postoperative prognostic stratification using the Union for International Cancer Control (UICC) TNM 8th edition staging rules (UICC 8) may identify additional groups of patients who could…[Read more]

This method would provide great potential in applications which require high resolution volume imaging.A nanosecond-millisecond combined pulse laser (CPL) drilling method was proposed for drilling alumina ceramic. The total energy consumption of the CPL drilling was 1/7 of that of a conventional millisecond laser, and the drilling quality was…[Read more]

Doxorubicin is an anthracycline and one of the more effective chemotherapy agents used in the treatment of children, adolescents, and adults with osteosarcoma. Despite its effectiveness, cardiotoxicity is a major late effect that compromises the survival and quality of life of survivors of this and other cancers. Cardiotoxicity is the inability of…[Read more]

in English, Portuguese FUNDAMENTO Vários marcadores têm sido avaliados quanto a um potencial impacto nas decisões clínicas ou na predição de mortalidade na síndrome coronariana aguda (SCA), incluindo Netrina-1 e IL-1β. OBJETIVO Examinamos o valor prognóstico de Netrina-1 e IL-1β em pacientes com SCA (2 anos de acompanhamento). MÉTODOS Avaliamos…[Read more]

Colistin represents the last-line treatment option against many multidrug-resistant Gram-negative pathogens. Several lines of evidence indicate that aminoarabinosylation of the lipid A moiety of lipopolysaccharide (LPS) is an essential step for the development of colistin resistance in Pseudomonas aeruginosa. However, whether it is sufficient to…[Read more]

Instead, we find that the evolution of a short larval period promotes greater exploration of climatic space, leading to increased rates of climatic niche evolution across species having this trait. We propose that morphological and physiological differences associated with variation in larval stage length underlie the heterogeneous ability of…[Read more]