We also measured blood titers of anti-β2GPI antibody, splenic cell proliferative responses and cytokine secretions after β2GPI stimulation ex vivo. Finally, we determined in these mice, hematological, hepatic and renal toxicities of crassolide. Crassolide after LPS stimulation suppressed DC maturation and secretion of tumor necrosis factor (…[Read more]

Acid rain promoted soil N2O emission in the coniferous and broadleaved mixed forest, but without significant difference among the treatments. Under the scenario of increasing acid rain, soil N2O emission fluxes in typical subtropical southern China forests would increase, and the magnitude of such increase was different among forest types.To…[Read more]

This study investigates water quality along the river Liffey in Dublin city with the help of citizen scientists, including the community of river users such as paddle boarders and those accessing the river from the bank. The primary objective was to evaluate water quality near sources of pollution observed by citizens, while filling data gaps for…[Read more]

Charge transfer is expressed in terms of ensembles of ionic state basis densities of individual atoms, and charge polarization, in terms of atomic excited-state basis densities. This provides a highly compact yet general representation of the force field, encompassing both local and system-wide effects. Charge rearrangement is realized through the…[Read more]

Using the same techniques for the first time in impacted watersheds, we find that only 24%-63% of the EOF can be explained by targeted PFAS and oxidizable precursors. Our work thus indicates the presence of large non-AFFF organofluorine sources in these coastal watersheds.Cyclic adenosine monophosphate (cAMP) is an important secondary messenger…[Read more]

Further, this could cause compensatory frameshift forms to branch in different locations in the protein and nucleotide trees, which may obscure the correct interpretation of phylogenetic relationships between variant viruses.

Our results imply that the compensatory frameshift is one of the mechanisms driving the rapid protein evolution of…[Read more]

Further research into synergistic effects of sequential radiotherapy and anti-angiogenesis therapy may provide an advantage in anticipating severe sequelae.While posterior reversible encephalopathy syndrome (PRES) is often characterized by an inflammatory cerebrospinal-fluid (CSF) profile, knowledge of immune cell patterns in PRES is lacking.…[Read more]

Rhinoliths are rare calcified entities in the nasal fossa, frequently originating around a nidus near the midway point in the inferior meatus, where the passage is the narrowest. They can be clinically asymptomatic and undetected for years. In this study, we present a rare case of large rhinolith mimicking atypical odontogenic pain in a…[Read more]

In response to chromatin bridges, the chromosomal passenger complex (CPC) delays completion of cytokinesis (abscission) to prevent chromosome breakage. Here, we discuss recent findings from our lab showing that an ATM-CHK2-INCENP pathway imposes the abscission checkpoint in human cells by regulating CPC midbody-localization.Recently we showed that…[Read more]

In age groups less then 44 years old, US with 98% had more sensitivity than CR with 89%. Conclusion Results showed that there is no significant difference in diagnostic value of US in bone erosion in patients with rheumatoid arthritis, in comparison with CR in terms of gender and diagnosis for the existence of erosions; however, in determining the…[Read more]

A foreign body in the respiratory tract is one of the common accidental injuries of children in our country, and is usually an important and serious event. Injuries caused by foreign substances in the respiratory tract seriously threaten the health and life of children in Korea and are a great challenge for parents as well. In the process of…[Read more]