This study carries out a detailed full-scale investigation on the strong wind characteristics at a cable-stayed bridge site and associated buffeting response of the bridge structure during construction, using a field monitoring system. It is found that the wind turbulence parameters during the typhoon and monsoon conditions share a considerable…[Read more]

The migration and invasion of colon cancer cells were considerably promoted by overexpressed NEAT1. Both NEAT1 and IGF2 bound to miR-185-5p. CONCLUSION NEAT1 upregulate IGF2 expression through absorbing miR-185-5p to enhances the migration and invasion of colon cancer cells. © 2020 The Authors. Molecular Genetics & Genomic Medicine published by…[Read more]

BACKGROUND β-cell dysfunction is one of the core pathogenetic mechanisms of type 2 diabetes mellitus (T2DM). However, there are currently no effective therapeutic strategies to preserve β-cell mass and function. The role of islet macrophage phenotype reprogramming in β-cell dysfunction has attracted great attention. Given that advanced gl…[Read more]

The first asymmetric total synthesis of three structures proposed for mycobacterial diacyl trehaloses, DAT1, DAT2, and DAT3 is reported. The presence of two of these glycolipids, DAT1 and DAT3, within different strains of pathogenic M. tuberculosis was confirmed, and it was shown that their abundance varies significantly. In mass spectrometry,…[Read more]

OBJECTIVE The aim of the study was to evaluate the effect of slice thickness, iterative reconstruction (IR) algorithm, and kernel selection on measurement accuracy and interobserver variability for semiautomated renal cortex volumetry (RCV) with multislice computed tomography (CT). METHODS Ten patients (62.4 ± 17.2 years) undergoing abdominal…[Read more]