41; 95%CI 0.42-6.39

= 0.02). Patients with 25OHD <10 ng/ml were likely to be ventilated for 9 days longer (ß 9.27; 95%CI 7.24-11.02

< 0.001) and to have a 34% higher risk of 90-day mortality (HR 1.34; 95% CI 1.06-1.71

= 0.02) compared to patients with levels

10 ng/ml.

In patients with ARDS, vitamin D status is…[Read more]

There have been a few case reports and one small series of low grade papillary sinonasal (Schneiderian) carcinomas (LGPSC) which mimic papillomas but have overtly invasive growth and which occasionally metastasize. We describe the morphologic, clinical, immunohistochemical, and molecular features of five patients with LGPSC compared with eight…[Read more]

However, more and better evidence is still needed before a definite conclusion could be drawn.

Anakinra (Kineret®), an IL-1 receptor antagonist, is the first FDA-approved biologic drug for antagonizing IL-1 in patients with Rheumatoid arthritis. The less expensive production of this drug might help reduce the final therapeutic costs.…[Read more]

9 ± 357.5 LMHB, and at the same time the flexural strength reached 109.6 ± 4.6 MPa. The much improved permeability was attributed to the unique multilevel pore structures, and the enhanced flexural strength mainly originated from the strongly interfacial bonding, as evidenced by the trans-granular fracture behavior. Also, the ceramic membrane s…[Read more]