BRCA1- and BRCA2-associated hereditary breast and ovarian cancer syndromes are among the best-known and most extensively studied hereditary cancer syndromes. Nevertheless, many patients who proved negative at BRCA genetic testing bring pathogenic mutations in other suppressor genes and oncogenes associated with hereditary breast and/or ovarian…[Read more]

Removal of As can be achieved even under visible light, confirming the field applicability of low-cost FG materials.This paper proposes a sustainable and facile approach for the synthesis of photocatalysts in which shell waste is used as support material. The synthesized photocatalysts exhibited a significant performance in the mineralization of…[Read more]

53 μM, Ki = 0.36 μM, and KD = 12 nM.The prerequisites for maximizing the advantageous optical properties of colloidal semiconductor quantum dots (QDs) in biological applications are effective surface functionalization and bioconjugation strategies. Functionalization with dextran has been highly successful with some nanoparticle materials, but h…[Read more]

Cabo Verde aims to eliminate malaria by 2020. In the country, Plasmodium falciparum had been the main parasite responsible for indigenous cases and primaquine is the first line treatment of cases and for radical cure. However, the lack of knowledge of the national prevalence of glucose-6-phosphate dehydrogenase (G6PD) deficiency may be one of the…[Read more]

Valorization of food byproducts has attracted recently considerable attention. Citrus fruits provide considerable non-edible residues reach 80% in juice production. They are considered agri-wastes to comprise peel, pulp and seeds. Previous investigations have focused on peel and pulp to recover value-added products. The review presents for the…[Read more]

The main objective of this paper was to analyse the roadway, environmental, and driver-related factors associated with an overrepresentation of frequency and severity of run-off-the-road (ROR) crashes. The data used in this study refer to the 6167 crashes occurred in the section Naples-Candela of A16 motorway, Italy in the period from 2001 to…[Read more]

BACKGROUND AND AIMS Studies on the association between homocysteine and non-alcoholic fatty liver disease (NAFLD) have shown inconsistent results. Our study concerns the association of homocysteine with the histological severity of NAFLD, especially non-alcoholic steatohepatitis (NASH) and significant fibrosis (SF) after adjusting for other…[Read more]

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Performance of peritoneal cytologic sampling has gradually decreased following the 2009 staging revision in the United States. Our study suggests that peritoneal cytology evaluation at hysterectomy may be associated with improved survival in certain tumor groups.The luminal gastrointestinal tract can be a site of robust immune response in…[Read more]