Chronic hepatitis B virus (HBV) infection is a major cause of liver disease and cancer worldwide for which there are no curative therapies. The major challenge in curing infection is eradicating or silencing the covalent closed circular DNA (cccDNA) form of the viral genome. The circadian factors BMAL1/CLOCK and REV-ERB are master regulators of…[Read more]

Ground-level ozone (O3) pollution frequently co-occurs with drought and nitrogen (N) deposition during the growing season. It is important to understand how the carbon dynamics of plants respond to O3 pollution in drier and N-enriched environments. Here we present the patterns of non-structural carbohydrates and its components (soluble sugar and…[Read more]

Alternate approaches, such as the use of individual HLA-I-expressing cell lines, are more time consuming, and such cell lines are difficult to procure and standardize. see more The HLA-I beads are also useful to study HLA-I specificity and selectivity for other receptors and binding partners.Sarcomeres are extremely highly ordered macromolecular…[Read more]

The mean strain ratio for malignant and benign lymph nodes was 22.2±30.1 and 5.2±1.7, respectively (p less then 0.001). Resveratrol datasheet With a cut-off value of ≥2.47 of strain ratio, the sensitivity for malignancy was 75% and specificity was 65%. The combined use of positron emission tomography and lymph node score or strain ratio yie…[Read more]