To develop a method for slice-wise dynamic distortion correction for EPI using rapid spatiotemporal B

field measurements from FID navigators (FIDnavs) and to evaluate the efficacy of this new approach relative to an established data-driven technique.

A low-resolution reference image was used to create a forward model of FIDnav signal…[Read more]

Background The most commonly used switching ratio from parenteral to oral methadone is 12. Methadone is highly bioavailable and a lower ratio might result in similar analgesia with less toxicity. Objective To compare success and side effects with two ratios from parenteral to oral methadone 12 versus 11.2 in hospitalized patients with cancer pain.…[Read more]

The results of autophagic flux using chloroquine and RFP-GFP-LC3 analysis showed that the accumulation of autophagosome was not caused by the formation but by the impaired degradation. PFOS was capable of blocking the fusion between autophagosome and lysosome. PFOS caused dysfunction of lysosomes because it down-regulated Lamp2a and cathepsin D,…[Read more]

Compared with diabetic rats, treatment with ginkgolide B significantly decreased levels of inflammatory cytokines, improved oxidative stress via reducing MDA concentration, and elevating SOD activity in serum and increasing expression of SIRT1, HO-1, and p-AMPK. Further, ginkgolide B alleviated cardiac fibrosis by decreasing expression of TGF-β1,…[Read more]

th toxin-free conditions. Because glyphosate is one of the leading herbicides in the world, tolerant phenotypes may benefit from current agricultural practices. If these results apply to other toxicants, low toxin doses may increase the fitness of tolerant phenotypes in a way not previously anticipated.

Hordeum glaucum Steud. is an important…[Read more]

The circadian clock regulates many biochemical and physiological pathways, and lack of clock genes, such as Period (Per) 2, affects not only circadian activity rhythms, but can also modulate feeding and mood-related behaviors. However, it is not known how cell-type specific expression of Per2 contributes to these behaviors. In this study, we find…[Read more]

This paper constructs various measures of domestic and global uncertainty and provides a comprehensive study of their impacts on the Thai economy. Based on a small open economy VAR, global uncertainty delivers deeper and more long-lasting effects when compared to within-country ones. In addition, we find that uncertainty shocks first generate…[Read more]

045). Univariate analysis demonstrated a relationship between number of injections and 1-year reoperation (

< .001). On multivariate analysis, those receiving injections within 30 days preoperatively had increased rates of SSI (

= .034) and noninfectious wound complications (

= .006) compared with those with no injection or at other…[Read more]