Moreover, the transferred Irf4-deficient CD8+ T cells displayed low expression of transcription factors ID2 and T-bet that govern the terminal effector T-cell programmes, and high expression of transcription factor TCF1 that maintains the naïve-memory T-cell programmes. Hence, IRF4 deficiency in CD8+ T cells abrogates their terminal effector…[Read more]

Unlike other erythrocytic parasites, Babesia exploits unconventional lifecycle strategies that permit host cycles of different lengths to ensure survival in hostile environments. With the licensure of new blood screening tests, incidence of transfusion transmission babesiosis has decreased.

New Babesia species have been identified globally,…[Read more]

05). CD34+SFCs were more frequent in cysts than in tumors. Ultrastructurally, CD34+SFCs were identified for the first time in odontogenic lesions and showed characteristic bipolar/dendritic morphology.

Among examined stromal stem cell markers, only SOX2 distinguished tumors from cysts. CD34+SFCs may also contribute to the biological…[Read more]