Although the absolute numbers of children and adolescents attending the PED and being admitted decreased after lockdown, the acuity of illness of those attending appears to be higher.We hypothesized that jejunal mucosal tissue blood flow would decrease following norepinephrine (NE) administration in endotoxic shock. We aimed of this study to…[Read more]

Over two years, the difference in ppFEV

by smoke exposure among tezacaftor/ivacaftor users increased by 1.2% (7.6% to 8.8%, p<0.001). In both mixed effects and fixed effects regression models, tezacaftor/ivacaftor use was associated with improved ppFEV

among unexposed individuals (1.2% and 1.7%, respectively; p<0.001 for both) but provided…[Read more]

We provide evidence that not only high but also grey zone amyloid burden subtly impacts memory function. Therefore, in case a binary classification is required, we suggest using a relatively low threshold which includes grey zone amyloid pathology.Odorant-binding proteins (OBPs) are small soluble proteins whose biological function is believed to…[Read more]

We provide evidence that not only high but also grey zone amyloid burden subtly impacts memory function. Therefore, in case a binary classification is required, we suggest using a relatively low threshold which includes grey zone amyloid pathology.Odorant-binding proteins (OBPs) are small soluble proteins whose biological function is believed to…[Read more]

Hippo pathway components are structurally and functionally conserved and are notable for their role in controlling organ size. More diverse functions of the Hippo pathway have been recognized, including development, tissue homeostasis, wound healing and regeneration, immunity, and tumorigenesis. During embryogenesis, different signaling pathways…[Read more]

Thus experiments carried out on the investigated opportunistic pathogen indicate that the mechanism of action of the researched surfactants is different than in the case of the majority of known surfactants. Results presented in this paper significantly broaden the understanding on multifunctional cationic surfactants and their mechanism of…[Read more]

l studies and intervention efforts should consider the interactive effects of these commonly co-morbid exposures.Chytridiomycosis, caused by the chytrid fungus Batrachochytrium dendrobatidis (Bd), is a leading cause of global amphibian declines. Severe infections with Bd can lead to cardiac arrest, and mass deaths during epidemics have been…[Read more]