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Lyhne Pilgaard posted an update 5 hours, 49 minutes ago
Both modelling and NMR data pointed at restricted dynamics of local conformations which were ascribed to the presence of inter-residue hydrogen bonds and to steric restrictions. In addition, the good correlation between NOE data and calculated interatomic distances by molecular dynamics simulations validated potential energy functions used for…[Read more]
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Lyhne Pilgaard posted an update 2 days, 20 hours ago
Histone deacetylases (HDACs) have been revealed to be involved in cerebrovascular diseases, while the role of HDAC9 in intracranial aneurysm (IA) remains seldom studied. We aim to explore the role of the HDAC9/microRNA-92a (miR-92a)/Bcl-2-like protein 11 (BCL2L11) axis in IA progression.
Expression of HDAC9, miR-92a and BCL2L11 in IA…[Read more]
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