In our case, renal dysfunction was also observed when systemic lupus erythematosus was diagnosed 1 year after LAHPS. Our case emphasizes that early recognition of adrenal failure and careful long-term observation is required in patients with autoantibodies.

This patient with LAHPS developed rare adrenal failure due to adrenal haemorrhage, a…[Read more]

In mice, both Alprolix

and BeneFIX

bind Col4 with similar affinities (Kd~20-40nM) and show dose-dependent recoveries. As expected, the concentration of binding sites in the mouse calculated for Alprolix

(574nM) was greater than for BeneFIX

(405nM), due to Alprolix

binding to both Col4 and the endothelial cell neonatal Fc…[Read more]

Glioblastoma (GBM) is the most common and aggressive primary malignant brain tumor in adults. Natural Killer (NK) cells are potent cytotoxic effector cells against tumor cells inducing GBM cells; therefore, NK cell based- immunotherapy might be a promising target in GBM. T cell immunoglobulin mucin family member 3 (TIM3), a receptor expressed on…[Read more]