risk of cardiovascular events.

We demonstrate that PCSK9 and LRP5 contribute to lipid uptake. We also show that LRP5 participates in PCSK9 transport to the plasma membrane and that PCSK9 inhibition protects against agLDL-induced inflammation associated to the TLR4/NFκB pathway. These results offer new targets to prevent the progression of…[Read more]

, 95% CI 1.07-1.35). CONCLUSIONS Health information found on the internet was positively associated with both the decision to visit a physician and the decision not to visit a physician. However, the association of health information seeking with the decision to visit a physician was slightly stronger than the association with the decision not to…[Read more]

The environmental sources of microbial aerosols and processes by which they are emitted into the atmosphere are not well characterized. In this study we analyzed microbial cells and biological ice nucleating particles (INPs) in smoke emitted from eight prescribed wildland fires in North Florida. When compared to air sampled prior to ignition,…[Read more]

50, p  less then  .001), psychological well-being (difference 4.34, 95% CI 3.70; 4.98, Cohen’s d 0.55, p  less then  .001) and sleep-related QoL (difference -44.61, 95%CI -47.17; -42.05, Cohen’s d -1.44, p  less then  .001) at week 48 compared to baseline. At week 24 dCBT, compared to SHE, also reduced use of prescription and non-prescription…[Read more]

Recent studies in adult humans have reported correlations between individual differences in people’s Social Network Index (SNI) and gray matter volume (GMV) across multiple regions of the brain. However, the cortical and subcortical loci identified are inconsistent across studies. These discrepancies might arise because different regions of…[Read more]