Background Acute myeloid leukemia (AML) remains a major clinical challenge due to poor overall survival, which is even more dramatic in elderly patients. selleck TIGIT, an inhibitory receptor that interacts with CD155 and CD112 molecules, is considered as a checkpoint in T and NK cell activation. This receptor shares ligands with the…[Read more]

then 0.001), whereas patients were more likely to receive palliative chemotherapy in their last year if their caregivers were adult children or if they were aged ≤50 years. Significant variations in EOL treatment strategies were observed according to caregivers and patient age during the last year of life.BReast CAncer (BRCA) genes 1 and 2 were d…[Read more]

55 (95% CI 0.40-0.68). The mean differences between GoCheck Kids and chart acuities (0.010) were not significantly different (P= .319; ICC 0.59; 95% CI 0.45-0.71). The mean differences between HOTV-ATS and chart acuities (0.084) were significantly different (P < .001; ICC 0.66; 95% CI 0.53-0.76). The percentages of eyes with visual acuity measured…[Read more]