Alteration gradients were identified in both studied regions based on the distribution of diatoms, with the first axis of distance-based redundancy analyses (dbRDA) being related to nutrient enrichment and organic loads. Threshold Indicator Taxa ANalysis (TITAN) performed on diatoms sampled along environmental (dbRDA axis 1 and phosphate) and…[Read more]

Pressure reactivity index (PRx) and brain tissue oxygen (PbtO2) are associated with outcome in TBI. This study explores the relationship between PRx and PbtO2 in adult moderate/severe TBI. Using the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) high resolution ICU sub-study cohort, we evaluated…[Read more]

KGaA, Weinheim.AIM Phosphodiesterase 10A (PDE10A) inhibitors not only have antipsychotic-like effects but also cause cognitive enhancement without affecting extrapyramidal side effects in rodents, suggesting that PDE10A may be a novel approach for the treatment of schizophrenia. However, how a combination of PDE10A inhibitor with a currently…[Read more]

BACKGROUND Necrotizing enterocolitis (NEC) is the leading cause of death among preterm infants born at less then  30 weeks’ gestation. The incidence of NEC is reduced when infants are fed human milk. However, in many neonatal intensive care units (NICUs), it is standard practice to freeze and/or pasteurize human milk, which deactivates bio…[Read more]

Examples are provided that demonstrate how multi-organoid ‘body-on-a-chip’ systems may be used to model the interdependent metabolism and downstream effects of drugs across multiple tissues in a single platform. Such 3D in vitro systems represent a more physiologically relevant model for drug screening and will likely reduce the cost and failure…[Read more]

ide new avenues for studying sperm storage and sustaining fertility. © The Author(s). 2020.Background The identification of circulating biomarkers that closely correlate with Parkinson’s Disease (PD) has failed several times in the past. Nevertheless, in this pilot study, a translational approach was conducted, allowing the evaluation of the…[Read more]

© 2020, Shindyapina et al.In diverse organisms, nanostructures that coherently scatter light create structural color, but how such structures are built remains mysterious. We investigate the evolution and genetic regulation of butterfly scale laminae, which are simple photonic nanostructures. In a lineage of buckeye butterflies artificially…[Read more]

51; P less then .0001) in focal and global cerebral edema, particularly in patients with TBI, SAH, and ICH (r = .5, P less then .001; r = .5; P less then .0001; r = .6, P less then .0001, respectively). At discharge, 23.7% of patients achieved a GOS of 5 or 4, 65.0% reached a GOS of 3 or 2, and 11.9% died (GOS 1). CT-score of cerebral edema in all…[Read more]

A peak EQE of 21.6% is realized in the 2tCz2CzBn-based nondoped device with an extremely low turn-on voltage of 2.7 V, high color stability, a high brightness over 20 000 cd m-2, a narrow full-width at half-maximum of 70 nm, and CIE color coordinates of (0.167, 0.248). © 2019 The Authors. Published by WILEY‐VCH Verlag GmbH & Co. KGaA, We…[Read more]

A peak EQE of 21.6% is realized in the 2tCz2CzBn-based nondoped device with an extremely low turn-on voltage of 2.7 V, high color stability, a high brightness over 20 000 cd m-2, a narrow full-width at half-maximum of 70 nm, and CIE color coordinates of (0.167, 0.248). © 2019 The Authors. Published by WILEY‐VCH Verlag GmbH & Co. KGaA, We…[Read more]

Therefore, it is crucial to achieve a well-functioning collaboration between veterinarians and the police and prosecutors. The expertise of these authorities on animal welfare legislation should also be emphasized to improve the efficacy of criminal procedures.In a longitudinal retrospective study, we aimed to assess natural protein (NP) tolerance…[Read more]