Our outcomes supply a conceptual basis for devising small-molecule inhibitors to block infiltrative cancer migration.The photophysical properties, especially the intersystem crossing (ISC) of two heavy-atom-free BODIPY derivatives with twisted π-conjugated frameworks (benzo[b]-fused BODIPY, BDP-B; and [a]phenanthrene-fused BODIPY, BDP-P), are…[Read more]

Local anesthetics, including lidocaine (Lid), are widely used in clinical settings but new evidence suggested that they may induce strong neurological side-effects in human brains. In this work, we used an in vitro model to examine the functional modulations of a long non-coding RNA (lncRNA), LINC01347 on Lid-induced cytotoxicity in SH-SY5Y cells.…[Read more]

Local anesthetics, including lidocaine (Lid), are widely used in clinical settings but new evidence suggested that they may induce strong neurological side-effects in human brains. In this work, we used an in vitro model to examine the functional modulations of a long non-coding RNA (lncRNA), LINC01347 on Lid-induced cytotoxicity in SH-SY5Y cells.…[Read more]

05). However, the results of the structural equation model indicated than only the family factors influenced the risk behaviours of adolescents (p less then 0.05). The spatial distribution of the risk behaviours in male adolescent students and community risk variables surrounding the area where schools are located allows for the description of…[Read more]

To examine the association between IVC diameter and postpartum blood loss and whether the variations in IVC diameter, if present, stands as a useful marker in diagnosis of postpartum blood loss.

Prospective case control study was conducted in a University Teaching Medical Center in Afula, Israel, between November, 2018 and March, 2020. The…[Read more]

Nearly half of all marijuana users reported driving after use during the past 30 days, and did not differ between males and females. Prevalence of driving after using marijuana was significantly higher among heavy users (PR = 2.8; 95% CI 2.1-3.6). A higher prevalence of driving after drinking alcohol (PR = 1.7; 95% CI 1.5-1.9) was also found a…[Read more]

of multiple SSAs. Article impact statement Species status assessments can be improved by an ecosystem-based approach that groups imperiled species by shared habitats and threats.SNIPS stands for a membrane fabrication technique that combines the evaporation induced self-assembly of the block copolymers and the classical nonsolvent induced phase…[Read more]

Both low-pressure and atmospheric plasmas are useful in converting the precursor film into ZnO nanoparticles despite completely different mechanisms.Wood-plastic composites have emerged and represent an alternative to conventional composites reinforced with synthetic carbon fiber or glass fiber-polymer. A wide variety of wood fibers are used in…[Read more]

The the study data of 228 corpses of children and adolescents aged from 4 to 17 years with a precisely established time of death – from 2 to 15 hours are presented. Three age groups are identified 1st – from 4 to 7 years, 2nd – from 8 to 11th and 3rd – from 12 to 17 years old. As a result of the studies it was found that the response of muscles to…[Read more]

Cancer stem cells (CSCs) are a limited cell population inside a tumor bulk characterized by high levels of glutathione (GSH), the most important antioxidant thiol of which cysteine is the limiting amino acid for GSH biosynthesis. In fact, CSCs over-express xCT, a cystine transporter stabilized on cell membrane through interaction with CD44, a…[Read more]