Polyamides (PAs) are powerful DNA ligands that can bind the minor groove of DNA with high affinity and specificity. While the characterization of PA-DNA behavior has focused principally on hairpin PAs 6-8 rings in size, there is increasing evidence that their behavior does not necessarily reflect the complexities that are emerging from studies of…[Read more]

The amniotic fluid (AF) is a complex biofluid that reflects fetal well-being during development. AF con be divided into two fractions, the supernatant and amniocytes. The supernatant contains cell-free components, including placenta-derived microparticles, protein, cell-free fetal DNA, and cell-free fetal RNA from the fetus. Cell-free mRNA (cfRNA)…[Read more]

To investigate differences in the relative sizes of the ankle-stabilizing muscles in individuals with versus without flexible flat feet and to determine predictors of symptom severity.

This cross-sectional study included 30 patients with symptomatic flexible flat feet and 24 normal controls. The following were evaluated foot posture index,…[Read more]

Based upon the summit conversation, this is something that each PhD program will have to decide based upon its own purpose and the environment it is preparing graduates to occupy. Nevertheless, preparing for a too narrow and specific career trajectory may not accommodate flexibility in the marketplace.Due to the COVID-19 pandemic, nursing programs…[Read more]