Modified ultrafiltration (MUF) is still used after pediatric cardiopulmonary bypass (CPB) in some pediatric cardiac surgery centers to decrease transfusion requirements. Other potential benefits of MUF include clearance of inflammatory markers and improvement in myocardial function. Our hypothesis is that MUF will hemoconcentrate coagulation…[Read more]

The drug inhibits the in vivo growth of multiple KRASG12C -mutant cell line xenografts, causes tumor regression in patient-derived xenograft models, and shows striking responses in combination with other agents. It has also produced objective responses in patients with mutant-specific lung and colorectal cancer. In this review, we discuss the…[Read more]

Orbital metastasis from breast cancer is relatively uncommon and is not the dominant prognosis. While it can reduce a patient’s QOL through symptoms such as diplopia, visual impairment, and exophthalmos, evidence suggests that radiotherapy might improve these symptoms in a relatively short period. We report 3 cases of orbital metastasis from…[Read more]