Among prospect transporters investigated in genetically-engineered mouse designs, we provide proof for a critical part regarding the organic cation transporter 2 (OCT2) in satellite glial cells to oxaliplatin-induced neurotoxicity, and demonstrate that targeting OCT2 utilizing hereditary and pharmacological methods ameliorates intense and chronic…[Read more]

Herein, we report on a multi-biomarker method making use of old-fashioned cytogenetic biomarkers, DNA damage biomarkers and transcriptional microRNA (miR) biomarkers in conjunction with their prospective gene objectives to determine radiosensitivity in ataxia-telangiectasia mutated (ATM)-deficient lymphoblastoid cell outlines (LCL); ATM-proficient…[Read more]