Purpose Leukemia accounts for a significant mortality across the globe every year. The main objective of the present research work was directed towards studying the anticancer effects of scutellarin-a plant flavone, against K562 human leukemia cells, along with examining its effects on cellular apoptosis, cell cycle, cell migration and cell…[Read more]

DNA double-strand breaks (DSBs) are a particularly lethal form of DNA damage that must be repaired to restore genomic integrity. Canonical non-homologous end joining (NHEJ), is the widely conserved pathway that detects and directly ligates the broken ends to repair the DSB. These events globally require the two proteins that form the Ku ring…[Read more]

This paper addresses ethical, legal and psychosocial aspects of Global Kidney Exchange (GKE). Concerns have been raised that GKE violates the non-payment principle, exploits donors in low and middle-income countries, and detracts from the aim of self-sufficiency. We review the arguments for and against GKE. We argue that while some concerns about…[Read more]