Copyright © 2020 American Chemical Society.This article focuses on the flow assurance of waxy crude oil using an environmentally benign and cost-effective approach involving thermochemical reaction. The study incorporates experimental and simulation works to evaluate heat and pressure generation potentials and heat transfer efficiency of the…[Read more]

Survival of patients with congenital heart defects including increased right ventricular pressure load (i.e. Tetralogy of Fallot) or pulmonary hypertension is dependent on the function of the right ventricle (RV). RV remodeling has several effects with progressive transition from compensated status to heart failure. Transient receptor potential…[Read more]

The interaction between homochiral substituted perylene bisimide (PBI) molecule and the D enantiomer of phenylalanine amino acid was monitored. Spectroscopic transitions of PBI derivative in aqueous solution in the visible range were used to evaluate the presence of D-phenylalanine. UV-visible, fluorescence, FT-IR, and AFM characterizations showed…[Read more]

hould be considered.

Beckmannia syzigachne (Steud.) Fernald has become a dominant weed that has evolved resistance to major herbicides used in the wheat fields of rice-wheat double cropping areas of the middle and lower reaches of the Yangtze River, China. Seed dispersal occurs over long distances via irrigation water. As mechanical harvesting…[Read more]

The surge of SARS-CoV-2 has challenged health systems worldwide and efficient tests to detect viral particles, as well as antibodies generated against them, are needed. Specificity, sensitivity, promptness or scalability are the main parameters to estimate the final performance, but rarely all of them match in a single test. We have developed…[Read more]

Based on heat map and principal component analysis, the relationships among physiological traits and relative expression of salt-responsive genes were investigated. Remarkably, we observed a significant association between the relative expression of TaHKT1;5 with root K+ concentration and K+/Na+ ratio and with TaSOS1. Taken together, our study…[Read more]

A simple reordering of the reaction sequence allowed the improved synthesis of EIDD-2801, an antiviral drug with promising activity against the SARS-CoV-2 virus, starting from uridine. Compared to the original route, the yield was enhanced from 17 % to 61 %, and fewer isolation/purification steps were needed. In addition, a continuous flow pro…[Read more]

Not every osteotomy needs to have an anterolateral hinge; in fact, decreasing the tibial slope would be a disadvantage in the posterior cruciate ligament-deficient knee. However, for the ACL-deficient knee with varus malalignment, aiming to decrease the tibial slope using an anterolateral hinge could be considered during preoperative…[Read more]

Approximately 43% of the variation in MIC90 for colistin could be explained by AMU, and a one-day increase in administration of colistin increased MIC90 by 0.05 μg mL-1. In conclusion, the results suggest that the higher the use of antimicrobials in farms, the higher the MDR frequency and resistance to the highest priority critically important…[Read more]

In order to investigate the interaction and behavior of cationic and uncharged oximes, we performed here molecular docking, molecular dynamics simulations, and binding energies calculations of the known cationic oximes HI-6 and 2-PAM plus four uncharged oximes found in the literature, complexed with human AChE (HssACHE) conjugated with the nerve…[Read more]

Surprisingly, although C160 is the major sphingomyelin species, it was only increased in ORMDL3-KO, whereas all other N-acyl chain sphingomyelin species were significantly increased in ORMDL-TKO cells. Analysis of sphingoid bases revealed that although sphingosine was only increased 2-fold in ORMDL-TKO cells, levels of dihydrosphingosine,…[Read more]