Co-deletion of Bax rescued the Bcl-xLcKO phenotype, while co-deletion of Mcl-1 enhanced the phenotype. These findings show that CGNPs require BCL-xL to regulate BAX-dependent apoptosis, and that this role can be partially compensated by MCL-1. Our data further show that BCL-xL expression regulates MCL-1 abundance in CGNPs, and suggest that…[Read more]

The primary objective of the current study was to explore the adoption of different coping strategies among survivors of acid violence in Pakistan. CID44216842 The data were collected from survivors of acid violence till saturation point was reached with the help of four key informants through a semi-structured interview guide from March, 2019 to…[Read more]

03, 2.21) compared with non-asthmatic children. More importantly, this increased risk was even greater in children with moderate-to-vigorous physical activity 2 h/d (OR 3.92, 95% CI 1.56, 9.88), while a negative association was observed between asthma and underweight in children aged 9-12 years (OR 0.23, 95% CI 0.06, 0.92). Mediation analysis…[Read more]

cater for long-term care.

A reverse of the situation in 1990, NCDs are predicted to be the leading cause of deaths and metabolic risk factors are predicted to contribute to the highest proportion of deaths in 2040. NCDs could demand a major share of resources within the health sector requiring extensive multi-sectoral prevention measures,…[Read more]