Low back pain is amongst the leading causes of disability worldwide. The degenerative intervertebral disc (IVD) environment contains pathologically high levels of inflammatory cytokines and acidic pH hypothesized to contribute to back pain by sensitizing nociceptive neurons to stimuli that would not be painful in healthy patients. We hypothesized…[Read more]

For various reasons, some elderly patients with femoral neck fracture undergo delayed surgical treatment. There is little information about the effect of delayed treatment on postoperative hip function and quality of life. The aim of this study was to investigate the effect of delayed hip arthroplasty on hip function, quality of life, and…[Read more]

For various reasons, some elderly patients with femoral neck fracture undergo delayed surgical treatment. There is little information about the effect of delayed treatment on postoperative hip function and quality of life. The aim of this study was to investigate the effect of delayed hip arthroplasty on hip function, quality of life, and…[Read more]

Retinal ganglion cells (RGCs) serve as the connection between the eye and the brain, with this connection disrupted in glaucoma. Numerous cellular mechanisms have been associated with glaucomatous neurodegeneration, and useful cellular models of glaucoma allow for the precise analysis of degenerative phenotypes. Human pluripotent stem cells…[Read more]

The source code is available at “https//github.com/yushanqiu/yushan.qiu-szu.edu.cn”.We herein report the distal γ-C(sp 3 )-H olefination of ketone derivatives and free carboxylic acids. Fine tuning of our previously reported imino-acid directing group and use of the ligand combination of mono- N -protected amino acid (MPAA) ligands and…[Read more]

in English, French S’il y a bien un domaine où les annonces pleuvent en matière de développement de l’intelligence artificielle (IA), c’est le secteur de l’imagerie médicale au sens large du terme (regroupant la radiologie, la médecine nucléaire et la radiothérapie). Les applications, encore souvent uti¬lisées dans des niches précises, ont te…[Read more]

These findings indicate that honeycomb-like gelatin scaffolds can promote the survival and chondrogenic differentiation of HUCMSCs to form hyaline-like cartilage. © 2020 Wiley Periodicals, Inc.To clarify the clinicopathological features of colorectal cancer in older people, systematic studies considering age, sex, and the tumor locus is needed.…[Read more]

09, 0.43, 0.45 and 0.23, respectively). However, fetal MRI was more accurate for the detection of normal anatomic findings in cases with suspected microcephaly, macrocephaly and craniosynostosis in NS when pooled together (p = 0.007). Furthermore, MRI also seemed to be advantageous in CC & CSP anomalies though it was not validated by statistical…[Read more]