We addressed issues by deliberate study design decisions and engagement with online community advocates.

Using social media to recruit hard-to-reach populations may be a successful way to engage them in research. Although researchers may remain compliant with the institutional review board of their facilities and are faithful to the tenets…[Read more]

32 (1.22-1.43),

<0.001). At four hours, 19·6% (12·9-27·9) of the ‘Yes’ group had attained a target RASS of -1, 0 or 1, compared to 13·6% (8·0-21·0) of those in the ‘No’ group. This proportion increased to 55·6% (46·1-64·9) at 24h compared with 44·9% (35·6-54·4) in the ‘No’ group.

Ceasing sedative infusions as soon as possible, i…[Read more]