Radiographs are integral in evaluating implant space and inter-root distance. The purpose of this report is to introduce a method for evaluating the 3D root position with minimal radiation using a 3D tooth model composed of an intraoral-scanned crown and a cone-beam computed tomography (CBCT)-scanned root.

Intraoral scan and CBCT scan of the patient were obtained before treatment. In the CBCT image, tooth segmentation was performed by isolating individual teeth from the maxillary and mandibular alveolar bone using software program. The 3D tooth model was fabricated by combining segmented individual teeth with the intraoral scan.

A post-treatment intraoral scan was integrated into the tooth model, and the resulting position of the root could be predicted without additional radiographs. It is possible to monitor the root position after a pretreatment CBCT scan using a 3D tooth model without additional radiographs.

The application of the 3D tooth model benefits the patient by reducing repeated radiation exposure while providing the clinician with a precise treatment evaluation to monitor tooth movement.

The application of the 3D tooth model benefits the patient by reducing repeated radiation exposure while providing the clinician with a precise treatment evaluation to monitor tooth movement.

We assessed the efficacy and safety of repository corticotropin injection (RCI; Acthar

Gel) for persistently active systemic lupus erythematosus (SLE) despite use of moderate-dose glucocorticoids.

This multicenter, double-blind, randomized, placebo-controlled study enrolled patients ≥ 18years with active SLE and moderatetosevere rash and/or arthritis despite stable glucocorticoid doses (7.5-30mg/day prednisone equivalent) and antimalarials for ≥ 4weeks and/or immunosuppressants for ≥ 8weeks before screening. Stable glucocorticoid doses were required through week 16 with optional taper from weeks 16 to 24. Patients were randomized (11) to 80 U RCI subcutaneously or placebo every other day to week 4, then twice weekly to week 24. Endpoints included the proportion of SLE Responder Index (SRI)-4 responders at week 16; changes from baseline to week 16 in 28 Swollen Joint Count/Tender Joint Count (28 SJC/TJC) and Cutaneous Lupus Erythematosus Disease Area and Severity Index (CLASI)-Activity score; and changestifier NCT02953821.Adopting methodologies utilizing exogenous data from ancillary stations for determining crop water requirement is a suitable approach to exempt local shortcomings due to the lack of meteorological data/stations. Meanwhile, soft computing techniques might be suitable tools to be used with such data management scenarios. The present paper aimed at evaluating the generalizability of the gene expression programming (GEP) technique for estimating reference evapotranspiration (ET0) through cross-station assessment and exogenous data supply, using data from Turkey and Iran. The GEP-based models were established and learnt using data from 10 stations in Turkey, and then the developed models were tested (validated) in 18 stations of Iran with considerable latitude differences. Different time periods (beginning and the end of time series) were selected for the training and testing stations so that there was no overlap among the dates of the events in both the groups. A comparison was also performed between the GEP models and the corresponding commonly used empirical equations. The obtained results revealed that the generalized GEP models presented promising outcomes in simulating daily ET0 values when they were trained and tested in quite distant stations with different chronological periods of the applied parameters. The performance accuracy of the empirical equations calibrated using exogenous data was reduced in comparison with their original (non-calibrated) versions. Further, although the generalization ability of the GEP models was reduced when the climatic context of the training-testing stations was different, the overall performance accuracy of those models was higher than those of the commonly used classic empirical equations.Determining water ecological carrying capacity (WECC) is of great significance to ensure inter-regional green development. This study presents a comprehensive evaluation framework for WECC assessment in the Yangtze River Economic Zone (YREZ), China. Effects of water resources, socio-economic, and ecological elements on WECC can be evaluated based on multi-criteria decision analysis. Zongertinib Gini and unbalance coefficients are used for measuring the regional fairness between WECC and socio-economic development. Surface water production pressure (SWPP) and groundwater pollution risk (GPR) are further regarded as indicators for expressing water resources constraint on shale gas extraction in the YREZ. Results disclose that the average WECC level decreases from 0.439 in 2000 to 0.4007 in 2016, which is the opposite of the changing trend in the Beijing-Tianjin-Hebei Region. A high WECC level appears in Zhejiang (0.5126) with a good state, but that of Guizhou (0.3983), Anhui (0.3968), Hunan (0.3914), and Chongqing (0.3651)ion) with slight modifications according to their actual situations for supporting water resource managers and government with decision making.A simple oxidation method for preparing CuO nanodisks on a flexible Cu sheet is presented. The crystal structure of as-prepared CuO nanodisks was analyzed by X-ray diffraction. The elemental composition and surface morphology were documented by X-ray photoelectron spectroscopy, scanning, and transmission electron microscopy. The photocatalytic performance of flexible Cu/CuO nanodisks was tested to mediate the degradation of RhB and MB dyes. After 2nd recycling, an in situ transformation of the nanodisk surface leads to electron transfer between the conduction bands of Cu2O and CuO phase, accelerating the degradation of the dyes due to a more favorable electron-hole separation under different band gap engineering. The optical and electrochemical impedance analyses were conducted to examine the efficiency of photogenerated charge carrier separation. Additionally, in the photodegradation system of Cu/CuO nanodisks, the generation of superoxide radical (·O2-) is responsible for the dye degradation under daylight irradiation.