Feo is the most widely conserved system for ferrous iron transport in prokaryotes, and it is important for virulence in some pathogens. However, its mechanism of iron transport is not fully understood. In this study, we used full-length Vibrio cholerae FeoB (VcFeoB) as a model system to study whether its enzymatic activity is affected by…[Read more]

Electrokinetic remediation is a widely admitted technology forrectifying heavy metal-contaminated soil. Various technologies have been effectively developed to improve the metal removal efficiency of contaminated soil by electrochemical treatment alone or in combination with other remediation technologies. The working components for electrokinetic…[Read more]

In the past decades, the world has experienced several major virus outbreaks, e.g. West African Ebola outbreak, Zika virus in South America and most recently global coronavirus (COVID-19) pandemic. Many vaccines have been developed to prevent a variety of infectious diseases successfully. However, several infections have not been preventable so…[Read more]

12b80 combines doxorubicin bound to a bone targeting hydroxybisphosphonate vector using a pH-sensitive linker, designed to specifically trigger doxorubicin release in an acidic bone tumor microenvironment. This phase I study aimed to determine the safety and toxicity profiles of 12b80 in dogs with naturally occurring osteosarcoma, with the…[Read more]

In brief, hBD3 and LL-37 induce a similar response in pneumococci and especially, changes in proteins with annotated transporter and virulence function have been identified. However, LL-37 causes changes in the abundance of cell surface modification proteins that cannot be observed after treatment with hBD3. Interestingly, CTAB induces unique…[Read more]

Even in clear ocean water, underwater optical wireless communication (UOWC) is impaired not only by absorption and scattering, but also by oceanic turbulence and dynamic pointing errors which result in a fading channel, degrading the bit error rate (BER) performance. In this paper, for the first time, we quantify analytically the trade-off between…[Read more]

To match the reform of hospice development in China, this study aimed to construct an indigenized health providers’ Knowledge, Attitude and Practice of Hospice Care (KAPHC) Scale in China with good validity and reliability.

We used three steps to develop the scale, establishing items-pool firstly based on literature review and expert…[Read more]

To match the reform of hospice development in China, this study aimed to construct an indigenized health providers’ Knowledge, Attitude and Practice of Hospice Care (KAPHC) Scale in China with good validity and reliability.

We used three steps to develop the scale, establishing items-pool firstly based on literature review and expert…[Read more]