14, 95% CI – 2.75 to 0.47, p = 0.162) but in the secondary outcome (G-SAS – 3.14, 95% CI – 0.24 to – 6.04, p = 0.03). Only 6.7% of the participants dropped out during follow-up and 77% of the GAMBOT group participants (74/96) continued to participate in the intervention throughout the 28-day period. Integrating intervention into a chatbot feature…[Read more]

BACKGROUND Microsatellite instability (MSI) has recently emerged as a predictive pan-tumor biomarker of immunotherapy efficacy, stimulating the development of diagnostic tools compatible with large-scale screening of patients. In this context, noninvasive detection of MSI from circulating tumor DNA stands as a promising diagnostic and…[Read more]

Fungiid corals (Cnidaria Anthozoa Scleractinia) occur at isolated locations scattered throughout the eastern tropical Pacific. They can be reef-associated but are often found on sand and rubble substrata distant from reef coral habitat. Cycloseris curvata is known in this region from the southern Gulf of California, through Mexico, Costa Rica, and…[Read more]